The effect of postoperative 3 month home enteral nutrition on health related quality of life and nutritional status of esophageal cancer patients after receiving Ivor Lewis minimally invasive esophagectomy.
Completed
- Conditions
- utritional support after esophagectomyNutritional, Metabolic, Endocrine
- Registration Number
- ISRCTN63015230
- Lead Sponsor
- Second Affiliated Hospital of Zhejiang University School of Medicine
- Brief Summary
1. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/29222890 (added 24/01/2019)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
1. Diagnosed with esophageal and esophagogastric junction cancer
2. Deemed suitable for potentially curative resection with intrathoracic anastomosis
Exclusion Criteria
1. Patients with unresectable tumors
2. Patient older than 80 years old
3. Patients that needed cervical incision and anastomosis
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> 1. The nutritional status, measured using the PG-SGA standard questionnaire, BMI, Albumin and Hemoglobin within 3 days prior to surgery, 2 weeks and 3 months after operation<br> 2. Quality of life, measured using the European Organization for Research and Treatment of Cancer (EORCT) general quality of life questionnaire (QLQ-C30) within 3 days prior to surgery, 2 weeks and 3 months after operation<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Outcomes for different surgical procedures , measured using the total hospital stay, time in the ICU, morbidity and mortality within 30 days<br> 2. Pain after surgery, measured using visual analogue score (VAS) until day 3 after surgery<br> 3. Complications after surgery, measured using pneumonia, chylothorax, vocal-cord paralysis, wound infection needing reoperation, anastomotic leakages, cardiac insufficiency, ileus need stop enteral nutrition and jejunostomy site enterocutaneous fistula<br> 4. Pathological results, measured using pathological tumor-node-metastasis classification, resection and circumferential margins and the number of lymph nodes retrieved<br>