跳至主要内容
临床试验/NCT03677635
NCT03677635已完成不适用

Is There a Relationship Between Memory for Past Events and Motivation for Future Activities?

King's College London4 个研究点 分布在 1 个国家目标入组 31 人开始时间: 2017年5月18日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
31
试验地点
4
主要终点
Post-Intervention Motivation Score

研究概览

简要总结

People with a diagnosis of psychosis often experience low motivation and pleasure when thinking about doing future activities. This leads, quite understandably, to doing fewer activities they used to enjoy and not taking up opportunities to do new activities. One model suggests that this may be partly due to difficulties using memories of previous events to help boost motivation and anticipation before a future activity. Research shows that people with psychosis may recall previous events in less detail. These memories therefore may not be as helpful as they could be for motivation. This study will investigate this by asking people with experience of psychosis and low motivation who are seen by a care team in South London and Maudsley NHS Trust to attend two research sessions. In the first session the participants will be asked to recall memories of events from their lives and the researcher will assess how detailed the memories are and how much the participant refers to the past and future. Alongside this task the participants will also be asked to complete measures of symptoms such as low pleasure and motivation as well as a measure of depression. These will be used to find out if the detail and specificity of the memories are related to these symptoms in people with psychosis. The second half of the study will then investigate whether additional prompts to support positive memory retrieval can increase the specificity of this and subsequently improve mood, motivation and self-belief. Participants will be randomised to one of two groups. The clinical group will be guided through their memory recall using prompts and a control group will be asked to recall positive memories without prompts. If the investigators show that supporting memory recall is beneficial then memories for past events may be an important target for future therapies.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
Single (Participant)

入排标准

年龄范围
18 Years 至 65 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • A diagnosis of non-affective psychosis (as determined by medical records).
  • Above 18yrs old.
  • A score of at least 18 on the Clinical Assessment Interview for Negative Symptoms.
  • A sufficient command of the English language to engage with the research materials

排除标准

  • Lack of capacity to provide informed consent.
  • Primary diagnosis of intellectual disability, head injury, substance misuse or known organic cause of psychosis

研究组 & 干预措施

Intervention

Experimental

Guided autobiographical memory recall to enhance specificity and links to the future.

干预措施: Guided Autobiographical Memory Recall (Behavioral)

Control

No Intervention

Recall without prompts or psychoeducation video.

结局指标

主要结局

Post-Intervention Motivation Score

时间窗: Immediately after completing the intervention

A rating on a visual analogue scale assessing motivation to repeat the same activity recalled in the future. The scale is rated from 0-100 and a higher score indicated better outcome.

次要结局

  • Post-Intervention Anticipatory Pleasure(Immediately after completing the intervention)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (4)

Loading locations...

相似试验