the study of Electro-convulsive therapy on psychiatric patients to understand its effect on clinical symptoms and prognosis
- Conditions
- Health Condition 1: F01-F99- Mental, Behavioral and Neurodevelopmental disorders
- Registration Number
- CTRI/2023/11/060220
- Lead Sponsor
- Maulana azad medical college
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
patients with catatonia, mania, depression and schizophrenia (diagnosed by ICD-10 criteria) who are planned for MECT (for refusal of food, severely violent or suicidal intention, poor response to medicines and other treatment
1. Patients with a history of epilepsy either current/remote with/ without medications
2. Pregnancy (to be ruled out with urinary pregnancy test)
3. Those that are on drugs which can modify seizure potential other than psychotropic
(e.g. amphetamines, aminophylline, isoniazid, cocaine, tramadol and
diphenhydramine)
4. Past history of significant major/ minor head injury as defined in Minor Traumatic
Brain Injury (MTBI) Working Group of American Academy of Neurology.
5. Those are not fit for MECT in terms of anaesthesia (e.g. allergic to aesthetic agents)
or other medical causes (e.g. recent spine injury, dislocation of joints, brain tumour
with increased ICT, recent CVA, MI).
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To find out the average seizure threshold (ST) to achieve clinically optimal seizure for <br/ ><br>duration of more than 25 seconds in patients receiving MECTTimepoint: at baseline
- Secondary Outcome Measures
Name Time Method To study the attitude to MECT among patients and/ or family members & their rate <br/ ><br>of acceptanceTimepoint: at baseline;To study the effect of MECT in clinical outcome in patients of catatonia, mania, <br/ ><br>depression & schizophreniaTimepoint: at baseline;To study the rate & reason for discontinuation of MECT in our patients.Timepoint: at baseline;To study the side effect profile of MECTTimepoint: at baseline