Impact of Fat Distribution on Metabolic, Cardiovascular and Symptomatic Aspects in Postmenopausal Women
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postmenopausal Disorder
- Sponsor
- University of Sao Paulo
- Enrollment
- 45
- Locations
- 1
- Primary Endpoint
- Relationships between postmenopause and fat distribution
- Status
- Completed
- Last Updated
- 13 years ago
Overview
Brief Summary
The purpose of this study is to investigate anthropometric, metabolic, cardiovascular and symptomatic profiles in postmenopausal women.
Detailed Description
When aging, the body composition changes, leading to a reduction of muscle mass and strength, and to an increase in total body fat. These body composition changes have especially been observed in postmenopausal women, due to the hormonal changes taking place. After the menopause, the gynoid fat distribution with fat deposits in the gluteo-femoral region changes to an android fat distribution with an increased upper body fat, especially in the abdominal region. These consequences of the menopause associated with a decrease in aerobic capacity and reduced total energy expenditure may lead to the metabolic syndrome (MetS). The aim of this study was to investigate the anthropometric, metabolic, cardiovascular and symptomatic profile in gynoid and android postmenopausal women.
Investigators
Fernanda Rossi Paolillo
Federal University of São Carlos
University of Sao Paulo
Eligibility Criteria
Inclusion Criteria
- •Postmenopausal women
- •Caucasian
- •50-60 years of age
Exclusion Criteria
- •Neurological disease
- •Pulmonary disease
- •Cardiac disease
- •Oncological disease
- •Musculotendinous or articular injuries
- •Hormone replacement therapy
- •Cigarette smoking
Outcomes
Primary Outcomes
Relationships between postmenopause and fat distribution
Time Frame: Baseline
Anthropometric measurements: waist-to-hip ratio and body mass index
Secondary Outcomes
- Comparison of the body composition between android and gynoid postmenopausal women(Baseline)
- Comparison of metabolic parameters between android and gynoid postmenopausal women(Baseline)
- Comparison of quality of life between android and gynoid postmenopausal women(Baseline)
- Comparison of aerobic capacity between android and gynoid postmenopausal women(Baseline)