EMG Training for Altering Activation Patterns After Stroke

Not Applicable

• Conditions: Weakness, Muscle; Stroke; Coordination Lack
• Interventions: Other: Unilateral; Other: Bilateral

• Registration Number: NCT03619772
• Lead Sponsor: Shirley Ryan AbilityLab

Brief Summary

Evaluation of a new EMG controlled game to improve hand function in chronic stroke survivors.

Detailed Description

Increased impairment of the hand is commonly reported as an outcome occurring after a stroke. This impairment is due mainly to the decreased ability to modulate appropriate muscle activation patterns. Issues with appropriately modifying activation patterns can profoundly affect tasks of daily living. This study is evaluating a novel software focusing on retraining hand muscle activation patterns through an Electromyographic (EMG) controlled game. Stroke survivors with chronic, severe hemiparesis of the hand will participate in a longitudinal study consisting of 3 weeks of training. We hypothesize that stroke survivors will experience a decrease in time to complete a test of EMG control, as well as improvement in hand motor control.

Study Timeline

• Study Start: 2018-06-28
• Study First Submitted: 2018-08-03
• Study First Submitted QC: 2018-08-03
• Study First Posted: 2018-08-08
• Primary Completion: 2020-10-31
• Status Verified: 2022-05
• Last Update Submitted: 2022-05-02
• Last Update Posted: 2022-05-03
• Study Completion: 2022-10-31

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• Single, unilateral stroke at least 6 months prior to enrollment
• Moderate hand impairment defined by Stage 4 or Stage 5 on the Chedoke McMaster Stroke Assessment Scale

Exclusion Criteria

• Visual neglect or deficits (with inability to compensate)
• Upper extremity orthopedic conditions that interfere with movement
• Cerebellar stroke

Children, prisoners, or adult unable to provide consent will not be recruited. As the procedures pose no increased risk for pregnant women, we will not specifically exclude them.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Unilateral	Unilateral	Participants will control game using the more impaired upper limb.
Bilateral	Bilateral	Participants will control game using EMG from both upper limbs.

Primary Outcome Measures

Name	Time	Method
Change in mean completion time for timed test	Baseline and 3 weeks (immediately post intervention)	Time to complete movement to 16 randomized targets

Trial Locations

Locations (1)

Shirley Ryan AbilityLab; 🇺🇸 Chicago, Illinois, United States