Effects of Macronutrient Relations on Body Weight, Body Composition, and Cardiovascular Risk Markers in Overweight Patients Attending a Telemedically Guided Weight Loss Program
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 2
- 主要终点
- body weight
研究概览
简要总结
The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic syndrome. There is evidence that energy-restricted low-carbohydrate diets show greater weight loss and better improvement of cardiovascular risk markers compared to energy-restricted low-fat diets. Beside macronutrient relations, efficacy of weight loss programs depends on care and control. The investigators aim to investigate whether or not a carbohydrate-restricted telemedically guided weight loss program results in a more pronounced weight loss and influences metabolic risk markers more beneficial than a fat-restricted diet.
详细描述
see brief summary.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age 18-70 years
- •body mass index > 27 kg/m2
排除标准
- •history of cardiovascular symptomatology
- •cholelithiasis
- •urolithiasis
- •insulin dependent diabetes
- •pacemaker implantation
- •pregnancy
- •lactation
- •vegetarianism
结局指标
主要结局
body weight
时间窗: 12 months
次要结局
- fat mass(baseline, 12 months)
- waist circumference(12 months)
- blood pressure(12 months)
- blood lipids(12 months)
- parameters of glucose metabolism(12 months)