Evaluation of Desensitization Protocols in Reduction of Dentin Hypersensitivity: A Randomized Clinical Trial
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 32
- 试验地点
- 1
- 主要终点
- Level of cervical dentin hypersensitivity by using visual analog scale
研究概览
简要总结
The aim of this study is through a double blind randomized clinical trial, evaluate the effectiveness of different clinical protocols in the reduction of dentin hypersensitivity. The desensitization approach (single agent or associated agents) and the long-term effectiveness (baseline, 1 week, 2 weeks, 4 weeks, 12 weeks and 24 weeks) will be evaluated. Data will be collected, tabulated and submitted to statistical analysis.
详细描述
Dentin hypersensitivity is characterized as an acute and short-term pain with multifactorial etiology. This condition is a clinical challenge due to the different treatment protocols available. Therefore, the aim of this study is through a double blind randomized clinical trial, evaluate the effectiveness of different clinical protocols in the reduction of dentin hypersensitivity. Thirty-two patients with dentin hypersensitivity in at least three teeth will be selected.The teeth will be randomly divided into two different groups according to the desensitization approach (single agent with neural action; single agent with obliterating action; associated technique (neural and obliterator agents). The dentin hypersensitivity level will be evaluated immediately after desensitization and after 1, 2, 4,12 and 24 weeks. Data will be collected, tabulated and submitted to statistical analysis.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Healthy individuals
- •Both genres, interested in the treatment of Dentin Hypersensitivity
- •Patients with all teeth in their mouth
- •Patients who have at least three teeth with Dentin hypersensitivity in different quadrants
- •Good oral hygiene
排除标准
- •Caries or unsatisfactory restorations
- •Presence of periodontal disease and or parafunctional habits
- •Cracks or enamel fractures
- •Extensive or unsatisfactory restorations
- •Recent restorations involving the labial surface
- •Orthodontics
- •Pregnant women
- •Gastroesophageal disease presence
- •Uncontrolled systemic disease
- •Severe bruxism
- •Constant use of analgesic
- •Allergic response to dental products
研究组 & 干预措施
Neural agent
UltraEZ. Prophylaxis of the teeth; an application every 48 hours; 4 sessions
干预措施: UltraEZ (Drug)
Obliterator agent
Enamelast. Prophylaxis of the teeth; an application every 48 hours; 4 sessions
干预措施: Enamelast (Drug)
Associative approach
UltraEZ and Enamelast. Prophylaxis of the teeth; an application every 48 hours; 4 sessions. In each session, fistly the UltraEZ (neural agent) will be applied and after the Enamelast (obliterator agent.)
干预措施: Enamelast (Drug)
Associative approach
UltraEZ and Enamelast. Prophylaxis of the teeth; an application every 48 hours; 4 sessions. In each session, fistly the UltraEZ (neural agent) will be applied and after the Enamelast (obliterator agent.)
干预措施: UltraEZ (Drug)
结局指标
主要结局
Level of cervical dentin hypersensitivity by using visual analog scale
时间窗: 24 weeks
Evaluation of the reduction in dentin hypersensitivity levels by using visual analog scale with a 24 weeks follow up.
次要结局
未报告次要终点
研究者
PAULO VINICIUS SOARES
Professor
Federal University of Uberlandia