Analysis of the Influence of Desensitizing Treatments on the Pulp Inflammatory Response in Bleached Teeth
- Conditions
- Pulp Inflammation
- Registration Number
- NCT04548674
- Lead Sponsor
- Universidade Federal do Para
- Brief Summary
This randomized, controlled, blinded clinical trial evaluated the effectiveness of different desensitizing protocols in preventing pulp inflammation after bleaching treatment with 35% hydrogen peroxide (PH) (Whiteness PH 35%).
- Detailed Description
Thirty healthy third human molars extracted by orthodontic indication were randomized and allocated into five groups (n = 6): CN (negative control): without intervention; CP (Positive control): PH; PMB: PH + photobiomodulation with low power laser; CPP: PH + casein phosphopeptide phosphopeptide amorphous calcium phosphate (CPP-ACPF); NANO: PH + nanohydroxyapatite. The office whitening was performed in two sessions with a single application of 45 min and an interval of 48 hours between them. Pulp tissues were removed for immunohistochemical analysis. Immunostaining was performed for Caspase 3 using an Axio Scope.A1 microscope.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 18
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SEQUENTIAL
- Primary Outcome Measures
Name Time Method Pulp inflammation 3 days After extraction of third molars Evaluation of pulp inflammation through immunohistochemistry of the third molar whitening or not
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Universidade Federal do Pará
🇧🇷Belém, Pará, Brazil
Universidade Federal do Pará🇧🇷Belém, Pará, Brazil