To compare two aneasthetic drug ( ketamine and ketamine , propofol mixture) as an induction agent in short duration gynaecological surgeries .

Not Applicable

• Conditions: Health Condition 1: N921- Excessive and frequent menstruation with irregular cycle

• Registration Number: CTRI/2022/10/046679
• Lead Sponsor: Department of aneasthesiology sms jaipur

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: ot Yet Recruiting
• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

ASA grade I and II patients undergoing elective gynaecological surgical procedures of short duration ( < 30 minutes ) requiring general anesthesia.

Exclusion Criteria

ASA GRADE III IV and V Patients with hemodynamically unstable , history of allergy to drugs being used ,hepatic and renal impairment, history of epilepsy and sign of increased intracranial pressure , difficult bag and mask , pregnant female more then 20 weeks of pregnancy.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
To assess and compare the effects of ketamine and ketofol as an induction agent on hemodynamic parameters ( SBP, DBP, MAP, HR, R/R AND SPO2 ) FROM THE BASELINE.Timepoint: From pre induction and after induction at 1,3,5,15,20 and 30 minutes .

Secondary Outcome Measures

Name	Time	Method
To assess and compare the difference in the meantime to sleep (loss of verbal contact). <br/ ><br>Timepoint: time duration in seconds from start of giving induction agent to loss of verbal response;To assess and compare the difference in mean Numeric pain rating scale (NRS) pain <br/ ><br>score after recovery from effect of anaesthesia.Timepoint: NRS for pain assessment at 1 hour after induction .;To assess and compare the difference in proportion of incidence of respiratory events and <br/ ><br>postoperative complications.Timepoint: Assessment of Respiratory complications in intraoperative period and assessment of postoperative complications at 1 hour after induction.