Magnesium after cardiac surgery practice change audit

Completed

• Conditions: Electrolyte disturbance; Cardiovascular disease; CARDIAC SURGERY; Cardiovascular - Coronary heart disease; Surgery - Other surgery

• Registration Number: ACTRN12617001263381
• Lead Sponsor: Austin Health

Brief Summary

The strategy of a 10 mmol magnesium bolus followed by a continuous infusion over 12 hours achieved a more sustained and moderately elevated magnesium concentration in comparison to a single 20 mmol bolus, despite increased urinary losses of magnesium. Further studies are required.

Detailed Description

Not available

Study Timeline

• Study Start: 2017-09-01
• Study Completion: 2017-11-30
• Last Update Posted: 7 January 2019

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

Adult (aged 18 years or older) patients who are admitted to the intensive care unit following cardiac surgery.

Exclusion Criteria

- known renal impairment
- treating intensive care unit consultant feels that it is not in the patient's best interest to be treated with the new magnesium supplementation protocol

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Occurrence of atrial fibrillation - hospital stay[As documented in the patient's medical record as assessed from the time of admission to the intensive care unit through to discharge from the hospital];Occurrence of atrial fibrillation - Intensive care unit admission[As documented in the patient's medical record as assessed from the time of admission to the intensive care unit through to discharge from the intensive care unit]

Secondary Outcome Measures

Name	Time	Method
Duration of intensive care unit admisison[Number of days that patient is admitted to the intensive care unit following cardiac surgery.];Duration of hospital admission[Number of days that patient is admitted to the hospital following cardiac surgery.];Duration of mechanical ventilation[The total number of hours of mechanical ventilation in the intensive care unit following cardiac surgery.];Mean serum magnesium concentration[Mean serum magnesium concentration of the routine morning formal blood test during admission to intensive care ];Dose of magnesium sulphate administered[Total amount in mmol/L of magnesium sulphate administered to post-cardiac surgery patients during the intensive care admission]