Testing the effect of drug ketamine (anaesthetic agent) in reducing pain following surgery and opioid consumption by giving through erector spinae block.
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2024/03/064029
- Lead Sponsor
- All India Institute of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Patients undergoing Modified Radical Mastectomy
2. ASA 1-3
3. 18 – 70 years of age
Exclusion Criteria
1. Inability to communicate
2. Contraindications of Nerve Block
3. Chronic opioid or analgesic use
4. Allergic to study medications
5. BMI more than 35
6. Patients with CAD
7. Patients with preexisting dementia, h/o seizure disorder
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess postoperative pain by NRS score <br/ ><br>Timepoint: At 1hour, 2hours, 4hours, 8hours, 12hours, 24hours
- Secondary Outcome Measures
Name Time Method Time of activation of PCA pump <br/ ><br> Cumulative consumption of fentanyl administered through PCA Pump <br/ ><br> Acute postoperative neuropathic pain as assessed by DN4 Questionnaire <br/ ><br> Use of rescue analgesics <br/ ><br> Incidence of opioid induced adverse effects <br/ ><br> Post operative nausea & vomiting <br/ ><br> Pruritis <br/ ><br> Respiratory depression <br/ ><br> Length of hospital stayTimepoint: At 24hours, 48hours, 72hours