Development of a novel hypoxic training method using carbon dioxide.
- Conditions
- Healthy adults subjects
- Registration Number
- JPRN-UMIN000019621
- Lead Sponsor
- Ishinomaki Senshu University
- Brief Summary
A comparison of polysomnography (PSG), heart rate variability analysis, and oxygen desaturation indices (ODI) for low-oxygen trials (15.4% O2) and low-oxygen, high-carbon dioxide trials (15.4% O2, 1500 ppm CO2) was conducted. No statistical significance was found among Stages N1, N2, N3, and R. The heart rate variability analysis showed no statistical significance among RR interval (RRi), high frequency (HF), and the ratio of low frequency to high frequency (LF/HF). There was no statistical significance among blood oxygen saturation (SpO2), ODI3, and ODI4. The concentration of carbon dioxide (1500 ppm) in the room did not have an adverse effect on the physiological response while sleeping in a low-oxygen environment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Not provided
Outpatients judged by their physicians to be ineligible for participation in the study Anyone diagnosed with sleep disorder (International Classification of Sleep Disorders, Second Edition) Participation judged inappropriate by an investigator Unable to attend on any designated study days Unable to comply with the specified sleep/arousal rhythm
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Apnea
- Secondary Outcome Measures
Name Time Method Sleep structure, End-tidal carbon dioxide partial pressure: