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An Observational Study On Metabolic Syndrome Parameters In Schizophrenia Patients Treated With Atypical Antipsychotics

Completed
Conditions
Metabolic Syndrome X
Schizophrenia
Interventions
Other: No intervention
Registration Number
NCT00448630
Lead Sponsor
Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Brief Summary

The purpose of the study is to find and follow-up the metabolic syndrome parameters on patients administering atypical antipsychotics.

Detailed Description

Sampling Method Details: Group of patients using the same atypical anti-psychotic.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
328
Inclusion Criteria
  • Female and male patients diagnosed as schizophrenia by the Diagnostic and Statistical Manual of Mental Disorders.
  • Age between 18-45 years
  • Patients who started atypical antipsychotic drug treatment or patients who switched from the previous conventional or atypical antipsychotic treatment to another atypical antipsychotic drug treatment by the decision of their physicians.
Exclusion Criteria
  • Patients who are pregnant or considering pregnancy.

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Atypical Antispychotics (or second generation antipsychotics)No interventionPatients with schizophrenia who are currently receiving or are going to start a new treatment with atypical antipsychotics, ziprasidone, risperidone, quetiapine, olanzapine, aripiprazole, amisulpride.
Primary Outcome Measures
NameTimeMethod
Metabolic Syndrome Parameter Waist CircumferenceBaseline, 1 Month, 4 Months

Iterative measurement of waist circumference. Mean at timepoints.

Metabolic Syndrome Parameter TriglyceridesBaseline, 1 Month, 4 Months

Iterative measurement of triglycerides. Mean at time points

Metabolic Syndrome Parameter High Density Lipoprotein (HDL)Baseline, 1 Month, 4 Months

Iterative measurement of HDL. Mean at time points

Metabolic Syndrome Parameter Fasting Blood SugarBaseline, 1 Month, 4 Months

Iterative measurement of fasting blood sugar. Mean at time points.

Metabolic Syndrome Parameter Body WeightBaseline, 1 Month, 4 Months

Iterative measurement of body weight. Mean at time points.

Metabolic Syndrome Parameter Low Density Lipoprotein (LDL)Baseline, 1 Month, 4 Months

Iterative measurement of LDL. Mean at time points

Metabolic Syndrome Parameter Body Mass Index (BMI)Baseline, 1 Month, 4 Months

Iterative mean Body Mass Index at time points.

Metabolic Syndrome Parameter Total CholesterolBaseline, 1 Month, 4 Months

Iterative measurement of total cholesterol. Mean at time points.

Secondary Outcome Measures
NameTimeMethod
Metabolic Syndrome Parameter Weight by Treatment GroupBaseline, 1 Month, 4 Months

Iterative measurement of weight. Mean at time points.

Metabolic Syndrome Parameter Triglycerides by Treatment GroupBaseline, 1 Month, 4 Months

Iterative measurement of triglycerides. Mean at time points.

Metabolic Syndrome Parameter BMI by Treatment GroupBaseline, 1 Month, 4 Months

Iterative measurement of BMI. Mean at time points.

Metabolic Syndrome Parameter Waist Circumference by Treatment GroupBaseline, 1 Month, 4 Months

Iterative measurement of waist circumference. Mean at time points.

Trial Locations

Locations (28)

Ankara Numune Research Hospital

🇹🇷

Ankara, Turkey

Bolu Psychiatry and Neurology Hospital

🇹🇷

Bolu, Turkey

Eskisehir Osmangazi University

🇹🇷

Eskisehir, Turkey

Bakirkoy Mental Health Hospital, First Clinic of Neurosis

🇹🇷

Istanbul, Turkey

Sisli Etfal Research and training Hospital

🇹🇷

Istanbul, Turkey

Cukurova University Scool of Medicine

🇹🇷

Adana, Turkey

Ankara Oncology Research and Training Hospital

🇹🇷

Ankara, Turkey

Antakya Mustafa Kemal University School of Medicine

🇹🇷

Antakya, Turkey

Bakirkoy Psychiatry and Neurology Hospital

🇹🇷

Istanbul, Turkey

Marmara School of Medicine

🇹🇷

Istanbul, Turkey

Ankara Numune Training and Research Hospital Department of Psychiatry

🇹🇷

Ankara, Turkey

19 may University School of Medicine

🇹🇷

Samsun, Turkey

Adana Psychiatry and Neurology Hospital

🇹🇷

Adana, Turkey

Pfizer Investigational Site

🇹🇷

Trakya, Turkey

Pamukkale University School Of Medicine

🇹🇷

Denizli, Turkey

Elazig Mental Illness And Diseases Hospital

🇹🇷

Elazig, Turkey

Cerrahpasa School of Medicine

🇹🇷

Istanbul, Turkey

Istanbul University Istanbul School of Medicine

🇹🇷

Istanbul, Turkey

Samsun Mental Illness And Diseases Hospital

🇹🇷

Samsun, Turkey

Trakya University School of Medicine

🇹🇷

Trakya, Turkey

Ankara Diskapi Training and Research Hospital

🇹🇷

Ankara, Turkey

Erenkoy Psychology and neurology hospital

🇹🇷

Istanbul, Turkey

Selcuk University Medical School Department of Psychiatry

🇹🇷

Konya, Turkey

Manisa Mental Illness And Diseases Hospital

🇹🇷

Manisa, Turkey

Vakif Gureba Hospital, Department of Psychiatry

🇹🇷

Istanbul, Turkey

Ege University School Of Medicine

🇹🇷

Izmir, Turkey

Kayseri Public Hospital

🇹🇷

Kayseri, Turkey

Trabzon Numune Research Hospital

🇹🇷

Trabzon, Turkey

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