Comparing two drugs in two different routes for reducing the cardiovascular changes associated with laryngoscopy and intubation.
Phase 4
- Conditions
- Health Condition 1: K352- Acute appendicitis with generalized peritonitisHealth Condition 2: O- Medical and Surgical
- Registration Number
- CTRI/2021/04/032996
- Lead Sponsor
- KLE Dr Prabhakar Kore Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.ASA 1 and 2
2.Patients undergoing elective surgeries under general anaesthesia with endotracheal intubation.
3. Provides consent
Exclusion Criteria
1. Patient refusal or who are unable to give consent.
2. ASA physical status 3 or more.
3. Patients allergic to drug under study.
4. Patients undergoing emergency surgery.
5. Patients with nasal pathology.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Comparision of intranasal dexmedetomidine with intravenous preservative free lignocaine with respect to hemodynamic variables like Mean arterial pressure, Systolic blood pressure, Diastolic blood pressure and Heart rate.Timepoint: Pre induction for Dexmedetomidine <br/ ><br>0mins 10 mins 20 mins 30 mins <br/ ><br>Pre induction for Lignocaine <br/ ><br>0min 3mins <br/ ><br>Post induction for both dexmedetomidine and lignocaine <br/ ><br>atL-I 1min 2min 3min 4min 5min 7min 10min <br/ ><br>
- Secondary Outcome Measures
Name Time Method To determine the incidence of side effects and complications.Timepoint: 0 to 10 mins