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Change of Macular Pigment Optical Density After Intravitreal Triamcinolon Injection Treatment

Not Applicable
Conditions
Diseases of the eye and adnexa
Registration Number
KCT0004230
Lead Sponsor
The Catholic University of Korea, Seoul St. Mary's Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot yet recruiting
Sex
All
Target Recruitment
62
Inclusion Criteria

1. A person who meets the following criteria
(1) a person diagnosed with diabetic and macular edema
(2) inovolved at least one eye
(3) central macular thickness is 300 or more by optical coherence tomography
2. Adult, the age of twenty or more
3. Patients with visual acuity less than or equal to 20/40 (Snellen) in the pathologic eye
4. Patients who voluntarily decided to participate in the study and signed a consent form

Exclusion Criteria

1. Pregnant state
2. Previous vitrectomy history
3. Previous history of intravitreal triamcinolone injection due to diabetic macular edema
4. Macular edema caused by other than diabetes
5. Diagnosed or treatment for other ocular cormorbidity such as, Intermediate or advanced dry age related macular degeneration (ARMD), exudative ARMD, vitreous hemorrhage, retinal vein occlusion, uveitis, retinal dystrophy, ocular trauma, optic nerve atrophy, intraocular tumor, corneal opacity
6. Ongoing diagnosed or suspcious intraocular or periocular infection
7. Uncontrolled glaucoma, Intraocular pressure over 21mmHg even with appropriate use of intraocular pressure lowering agents. History of glaucoma surgery due to steroid induced glaucoma
8. Chronic alcoholics or psychiatric state that could affact the study process.
9. Patients who thought to be not able to complete study process or have a medical condition is unsuitable for study process by clinicion's opinion
10. Uptaking lutein or other medication which affect macular pigment optical density.

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
macular pigment optical density(MPOD) after 4, 12 weeks from intravitreal injection
Secondary Outcome Measures
NameTimeMethod
Central macular thickness;best corrected visual acuity
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