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A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s)

Completed
Conditions
Small Cell Lung Carcinoma
Carcinoma, Non-Small Cell Lung
Triple Negative Breast Carcinoma
Hepatocellular Carcinoma
Urothelial Carcinoma
Interventions
Registration Number
NCT03232593
Lead Sponsor
Hoffmann-La Roche
Brief Summary

This Phase 4, prospective, multicenter, non-interventional, regulatory post-marketing surveillance study will collect information on the the safety and effectiveness of atezolizumab under the clinical practice, and update the drug label approved by the MFDS in Korea.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
1758
Inclusion Criteria
  • Participants who are administered with atezolizumab for the locally approved indications
Exclusion Criteria
  • Participants with a known hypersensitivity to atezolizumab or to any of the excipients

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Participants who Receive AtezolizumabAtezolizumabParticipants who are administered with atezolizumab as per the local label and standard of care at physician's discretion will be observed for approximately 6 years.
Primary Outcome Measures
NameTimeMethod
Percentage of Participants With Adverse Events (AEs) and Serious AEs (SAEs)Approximately 6 years
Secondary Outcome Measures
NameTimeMethod
Percentage of Participants With Progressive Disease (PD) Assessed per RECIST 1.1Approximately 6 years
Percentage of Participants With Complete Response (CR) Assessed per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1)Approximately 6 years
Percentage of Participants With Stable Disease (SD) Assessed per RECIST 1.1Approximately 6 years
Percentage of Participants With Partial Response (PR) Assessed per RECIST 1.1Approximately 6 years

Trial Locations

Locations (55)

Dongnam Inst.of Radiological & Medical Sciences

🇰🇷

Busan, Korea, Republic of

Inje University Busan Paik Hospital

🇰🇷

Busan, Korea, Republic of

Inje university Haeundae Paik Hospital

🇰🇷

Busan, Korea, Republic of

Kosin University Gospel Hospital

🇰🇷

Busan, Korea, Republic of

Dong-A University Hospital

🇰🇷

Busan, Korea, Republic of

Pusan National University Hospital

🇰🇷

Busan, Korea, Republic of

Donga Uni Medical Center; Pulmonary

🇰🇷

Busan, Korea, Republic of

Pusan University Hospital

🇰🇷

Busan, Korea, Republic of

Pusan University Hospital; Hemato-oncology

🇰🇷

Busan, Korea, Republic of

Kyungpook National University Medical Center

🇰🇷

Daegu, Korea, Republic of

Keimyung University Dongsan Medical Center

🇰🇷

Daegu, Korea, Republic of

Daegu Catholic University Medical Center

🇰🇷

Daegu, Korea, Republic of

Gangneung Asan Hospital

🇰🇷

Gangwon-do, Korea, Republic of

Konyang University Hospital

🇰🇷

Daejeon, Korea, Republic of

Keimyung University Dongsan Hospital; Pulmonology

🇰🇷

Daegu, Korea, Republic of

Hallym University Medical Center Chuncheon Sacred Heart Hospital

🇰🇷

Gangwon-do, Korea, Republic of

Yonsei University Wonju Severance Christian Hospital

🇰🇷

Wonju-Si, Korea, Republic of

Uijeongbu St. Mary's Hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

Hallym University Sacred Heart Hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

CHA Bundang Medical Center

🇰🇷

Gyeonggi-do, Korea, Republic of

Soonchunhyang University Bucheon Hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

Bucheon St Mary's hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

Korea University Ansan Hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

St. Vincent's Hospital

🇰🇷

Gyeonggi-do, Korea, Republic of

Pusan National University Yangsan Hospital

🇰🇷

Gyeongsangnam-do, Korea, Republic of

Chonbuk National University Hospital

🇰🇷

Jeollabuk-do, Korea, Republic of

Hallym University Dongtan Sacred Heart Hospital

🇰🇷

Hwaseong Si, Korea, Republic of

Wonkwang University School of Medicine & Hospital

🇰🇷

Jeonlabuk-do, Korea, Republic of

Chonnam National University Hwasun Hospital

🇰🇷

Jeollanam-do, Korea, Republic of

Korea Cancer Center Hospital of Korea Institute of Radiological and Medical Sciences

🇰🇷

Seoul, Korea, Republic of

Korea University Anam Hospital

🇰🇷

Seoul, Korea, Republic of

Kangbuk Samsung Hospital

🇰🇷

Seoul, Korea, Republic of

Eunpyeong St. Mary's Hoapital

🇰🇷

Seoul, Korea, Republic of

Severance Hospital, Yonsei University Health System

🇰🇷

Seoul, Korea, Republic of

Severance Hospital, Yonsei University

🇰🇷

Seoul, Korea, Republic of

Soonchunhyang University Hospital

🇰🇷

Seoul, Korea, Republic of

Gangdong Kyung Hee University Hospital

🇰🇷

Seoul, Korea, Republic of

Hanyang University Medical Center

🇰🇷

Seoul, Korea, Republic of

VHS Medical Center

🇰🇷

Seoul, Korea, Republic of

Asan Medical Center

🇰🇷

Seoul, Korea, Republic of

Seoul St Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

Gangnam Severance Hospital

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Center

🇰🇷

Seoul, Korea, Republic of

Borame Medical Center

🇰🇷

Seoul, Korea, Republic of

ChungAng University Hospital

🇰🇷

Seoul, Korea, Republic of

Yeouido St. Mary's Hospital

🇰🇷

Seoul, Korea, Republic of

Korea University Guro Hospital

🇰🇷

Seoul, Korea, Republic of

Severance Hospital, Yonsei University Health System; Oncology

🇰🇷

Seoul, Korea, Republic of

Samsung Medical Centre; Division of Hematology/Oncology

🇰🇷

Seoul, Korea, Republic of

Ewha Womans University Mokdong Hospital; Urology

🇰🇷

Seoul, Korea, Republic of

Korea Uni Anam Hospital; Internal Medicine

🇰🇷

Seoul, Korea, Republic of

Ulsan University Hosiptal

🇰🇷

Ulsan, Korea, Republic of

Ulsan University Hospital

🇰🇷

Ulsan, Korea, Republic of

Pusan National University Yangsan Hospital; hemato-oncology

🇰🇷

Yangsan, Korea, Republic of

SoonChunHyang University Hospital Seoul

🇰🇷

Seoul, Korea, Republic of

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