IRCT20220220054079N1招募中3 期
Effect of deferoxamine injection on the Glasgow Outcome Scale in patients with severe traumatic brain injury: a double-blind, randomized controlled clinical trial
试验速览
- 阶段
- 3 期
- 状态
- 招募中
- 入组人数
- 68
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 years 至 65 years（—）
- 性别
- All
入选标准
- •Patients with severe traumatic brain injury
- •Patients with pure traumatic brain injury: having a score of less and equal to 3 on the Brain Abbreviated Injury scale; and a score of less than 3 on the Extracranial Abbreviated Injury scale
排除标准
- •Allergy to deferoxamine mesylate
- •Serum creatinine more than 2 mg/dL
- •Hemoglobin less than 7 g/L, or patients requiring transfusion therapy
- •A Glasgow Coma Scale score of 3 or 4 with bilateral fixed and dilated pupils
- •A known history of intracranial diseases
- •A known history of thrombocytopenia (platelet count less than 50×109/L)
- •Concurrent use of anti-coagulant or anti-platelet agents or history of coagulation disorders (international normalized ratio more than 1.4)
- •Concurrent use of iron supplements or prochlorperazine
- •Impaired hearing
- •Pregnant or lactating women
- •History of cardiopulmonary arrest and resuscitation
- •Blood disorders (e.g. thalassemia, iron deficiency anemia)
- •GFR less than 50 ml/min
- •History of heart failure
- •History of liver disease
研究者
相似试验
招募中
3 期
implication of Deferoxamine in the treatment of kienbock’s diseaseKienböck disease of adults.Adult osteochondrosis of carpal lunateIRCT2017073035382N1Vice Chancellor for research of Iran University of Medical Sciences10
已完成
3 期
deferoxamine and its cardiotoxicity effectsacute and chronic cardiopathy.Heart disease, unspecifiedIRCT2016080615666N5Vice chancellor of research, Shiaz Univeisity of Medical Sciences60
尚未招募
2 期
Efficacy and safety of triple iron chelator (deferoxamine, deferasirox, and deferiprone) versus dual iron chelator (deferoxamine and deferasirox) combination therapy for reducing iron overload in transfusion-dependent beta-thalassaemia with very high iron overload.ThalassaemiaSLCTR/2023/010Prof Anuja Premawardhena
已完成
2 期
Treatment of iron overload in thalassemia patientsThalassemia.Beta thalassaemiaIRCT2016041627412N1Vice Chancellor for research of Urmia University of Medical Sciences36
已完成
2 期
Effect of deferoxamin on strokeCondition 1: stroke. Condition 2: intracerebral haemorrhage.Cerebral infarction due to unspecified occlusion or stenosis of cerebral arteriesSequelae of intracerebral haemorrhageIRCT2013111915444N2Vice chancellor for research, Ahvaz Jondishapur University of Medical Sciences64