跳至主要内容
临床试验/NCT07208578
NCT07208578尚未招募不适用

Non-invasive Hemodynamic Monitoring in COPD Patients Admitted to the Respiratory Intensive Care Unit: Reliability, Clinical Utility, and Ventilation-related Hemodynamic Changes

Assiut University0 个研究点目标入组 96 人开始时间: 2026年1月30日最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
96
主要终点
Cardiac output (CO) measured by the electrical cardiometer (ICON®) in COPD patients admitted to the respiratory ICU.

研究概览

简要总结

This study investigates the reliability and clinical usefulness of non-invasive electrical cardiometry (ICON® device) in monitoring hemodynamic changes in COPD patients admitted to the respiratory intensive care unit (RICU).

详细描述

hemodynamic monitoring is critical in critically ill patients, especially those with COPD experiencing acute respiratory failure. Traditional invasive methods such as pulmonary artery catheterization are accurate but carry procedural risks. The ICON® device enables real-time, continuous, non-invasive assessment of parameters like cardiac output, stroke volume, systemic vascular resistance, and thoracic fluid content using thoracic bioimpedance. This prospective observational study will assess its reliability against clinical outcomes and evaluate the influence of different ventilation strategies (invasive, non-invasive, no ventilation) on hemodynamic changes. Data will be collected serially throughout ICU stay to determine ICON's contribution to optimizing patient management and risk stratification.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Age ≥ 18 years
  • Admission to RICU with COPD or COPD-related acute respiratory failure
  • Informed consent provided by patient or legal representative

排除标准

  • patients <18 years
  • Pregnant women
  • Injuries, burns, or skin conditions preventing electrode placement
  • Patients with uncontrolled seizures
  • Patients needing electrical DC shock
  • Refusal or withdrawal of informed consent

结局指标

主要结局

Cardiac output (CO) measured by the electrical cardiometer (ICON®) in COPD patients admitted to the respiratory ICU.

时间窗: Baseline

The change in cardiac output values during the ICU stay as measured non-invasively by the ICON device, reflecting hemodynamic status.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Yousef Tharwat Geris Qrqar

resident at the Chest Diseases and Tuberculosis Department

Assiut University

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