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A prospective cohort study to investigate the use of avb3-integrin imaging as a surrogate endpoint for therapeutic interventions in patients with myocardial infarction.

Conditions
Myocardial infarctionHeart FailureHartinfarctHartfalen
Registration Number
NL-OMON27835
Lead Sponsor
Maastricht University Medical Center
Brief Summary

/A

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
123
Inclusion Criteria

1. The subject has had no previous MI (a previous MI/scar could potentially result in tracer uptake and therefore interfere with the imaging outcome), presents with acute MI and has undergone coronary angiography during which percutaneous coronary intervention (PCI) or no intervention may be performed. The documentation of coronary anatomy and disease will be linked to the imaging outcome;

2. The subject is >18 years of age at study entry. Maximum age is 80 years, provided patients are in good condition;

Exclusion Criteria

1. The subject was previously entered into this study or has participated in any other IMP study within 30 days of study entry, since this could interfere with the medications tested;

2. The subject is scheduled to receive another IMP from time of entry into this study until completion of the follow-up period after the second injection proposed for this study, since this could interfere with the medications and endpoints tested;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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