Exploring the Effect of Footbaths on Increasing the Success Rates of in Vitro Fertilization and Its Associated Mechanism
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 80
- 试验地点
- 1
- 主要终点
- pregnancy rate
研究概览
简要总结
To evaluate the effectiveness of warm-water footbaths in enhancing pregnancy rates during IVF and to explore the underlying mechanisms involved.
详细描述
Additionally, this research will assess whether a complementary and alternative medicine (CAM) approach utilizing warm-water footbaths is effective in improving pregnancy rates for women undergoing IVF. Furthermore, the potential mechanisms by which footbaths may enhance IVF success rates will be elucidated.
The specific aims of this research proposal are as follows:
- To explore the correlation between health statuses, sleep quality, stress, and infertility incidence.
- To investigate the association between health statuses, sleep quality, stress, and multiple inflammatory indexes in infertile women, including:
2-1. Systemic immune inflammation index (SII) 2-2. Lymphocyte count (LC) 2-3. Platelet and neutrophil count product (PPN) 2-4. Platelet-lymphocyte ratio (PLR) 2-5. Neutrophil-lymphocyte ratio (NLR) 2-6. Lymphocyte-monocyte ratio (LMR) 3. The effects of Footbaths on Stress and Sleep:
To examine the effects of footbaths on reducing stress and improving sleep quality, which may enhance pregnancy success rates during IVF treatment in infertile women. 4. The impact on Inflammatory Markers:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women aged 18~45 years
- •diagnosed with male factor infertility
- •tubal factor infertility, or unexplained infertility, and undergoing an IVF treatment.
排除标准
- •participants having adenomyosis, severe endometriosis
- •a history of more than two IVF treatments
- •any comorbidity or uncontrolled systemic diseases such as hypertension, diabetes, chronic heart disease or chronic renal disease that can affect the treatment process.
结局指标
主要结局
pregnancy rate
时间窗: 28 days
IVF success rates in infertile women
次要结局
未报告次要终点
研究者
YA-WEN SHIH
Professor
National Taipei University of Nursing and Health Sciences