Epidemiology and Hospital Management of Patients With PROS in France: a PMSI Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 3,605
- 试验地点
- 1
- 主要终点
- Yearly Prevalence Rate
研究概览
简要总结
The purpose of this study was to estimate the incidence and prevalence of a group of genetic disorders known as PIK3CA-Related Overgrowth Spectrum (PROS) in France. Additionally, the study aimed to characterize patients, disease management, and costs associated with PROS. This study used data from the French National Hospitals Database, Programme de Médicalisation des Systèmes d'Information (PMSI). The study period was from January 2015 to December 2022.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 2 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Yearly Prevalence Rate
时间窗: Up to approximately 6 years
Yearly prevalence rate was calculated by dividing the number of identified patients with PROS by the total French population during the inclusion period. The inclusion period was from January 2017 to December 2022.
Yearly Incidence Rate
时间窗: Up to approximately 6 years
Yearly incidence rate was calculated by dividing the number of PROS newly diagnosed cases during the inclusion period (incident cases) by the total French population during the inclusion period. The inclusion period was from January 2017 to December 2022.
次要结局
- Number of Patients by Patient Characteristics(Baseline)
- Number of Comorbidities per Patient(Baseline)
- Number of Patients by PROS Diagnosis(Baseline)
- Average Length of Stay of Hospitalization(Baseline)
- Number of Patients by Type of PROS-related Technical Procedures(Baseline)
- Number of Patients by Type of Hospitalization(Baseline)
- Number of Patients by Hospitalization Severity(Baseline)
- Average Duration of Follow-up(Up to approximately 6 years)
- Number of All-cause Hospitalizations During the Follow-up Period(Up to approximately 6 years)
- Number of PROS-related Hospitalizations by Year of Follow-up(Up to approximately 6 years)
- Number of PROS-related Hospitalizations During the Follow-up Period(Up to approximately 6 years)
- Number of Patients With PROS-related Hospitalization During the Follow-up Period by Type of Hospitalization and Age Range(Up to approximately 6 years)
- Average Length of Stay of PROS-related Inpatient Hospitalization During the Follow-up Period(Up to approximately 6 years)
- Number of PROS-related Hospitalizations During the Follow-up Period by Level of Severity(Up to approximately 6 years)
- Number of All-cause External Technical Procedures and Visits During the Follow-up Period(Up to approximately 6 years)
- Number of Patients With at Least one All-cause External Technical Procedure and Visit During the Follow-up Period(Up to approximately 6 years)
- Number of External Technical Procedures and Visits of Interest During the Follow-up Period(Up to approximately 6 years)
- Number of Patients With an External Technical Procedure and Visit of Interest During the Follow-up Period(Up to approximately 6 years)
- Number of External Technical Procedures and Visits by Specialty of the Performing Healthcare Professional During the Follow-up Period(Up to approximately 6 years)
- Number of Emergency Room Visits not Followed by Hospitalization During the Follow-up Period(Up to approximately 6 years)
- Number of Patients With at Least one Emergency Room Visit not Followed by Hospitalization During the Follow-up Period(Up to approximately 6 years)
- Healthcare Resource Consumption Rate Per Patient-Year (PPY) During the Follow-up Period(Up to approximately 6 years)
- Healthcare Costs PPY During the Follow-up Period(Up to approximately 6 years)