RESolutie van Ontsteking in de Luchtwegen na Virale Expositie.
Completed
- Conditions
- Virus-induced exacerbations in allergic asthmatics.keywords: rhinovirus, exacerbation, allergy, asthma
- Registration Number
- NL-OMON22107
- Lead Sponsor
- Department of Pulmonology of the Academic Medical Center in Amsterdam
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 42
Inclusion Criteria
Allergic asthmatics:
1. Age between 18 and 40 yrs;
Exclusion Criteria
Allergic asthmatics:
1. Current smokers;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1. Common cold questionnaire;<br /><br>2. Asthma symptom score;<br /><br>3. FEV1;<br /><br>4. PC20 methacholine;<br /><br>5. Inflammatory cell numbers;<br /><br>6. Indoleamine 2,3-dioxygenase expression;<br /><br>7. Apoptotic markers.
- Secondary Outcome Measures
Name Time Method 1. Exhaled NO;<br /><br>2. ENose measurement;<br /><br>3. Coagulation parameters.