TNF Polymorphism and Implantation Rate

Completed

• Conditions: Infertility

• Registration Number: NCT02806934
• Lead Sponsor: Centre Hospitalier Universitaire de Nice

Brief Summary

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

Detailed Description

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Study Timeline

• Study Start: 2009-06
• Primary Completion: 2013-12
• Study Completion: 2013-12
• Study First Submitted: 2016-05-27
• Status Verified: 2016-06
• Study First Submitted QC: 2016-06-20
• Last Update Submitted: 2016-06-20
• Study First Posted: 2016-06-21
• Last Update Posted: 2016-06-21

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Female
• Target Recruitment: 120

Inclusion Criteria

• Women
• normal karyotype,
• age under 38 years
• serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l

Exclusion Criteria

• age under 18 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Implantation rate by ultrasound test	20 days after implantation
Implantation rate by biological test	20 days after implantation

Trial Locations

Locations (1)

Nice University Hospital; 🇫🇷 Nice, France