Insufficiency Fractures of the Knee: Insufficient of Nutrients or Cartilage?
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Correlation between subchondral insufficiency fractures (SIFKs) and coexisting conditions
研究概览
简要总结
This prospective cohort study is designed to investigate possible association(s) between subchondral insufficiency fractures (SIFKs) of the knee and pre-existing health, lifestyle, and/or musculoskeletal conditions. In doing so, this research may shed light on the underlying cause(s) of SIFKs. It is hypothesized that SIFKs of the knee are related to osteoarthritis, weak bone, and/or metabolic issues, rather than trauma.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Patients diagnosed with SIFK from ages ≥18 years old who seek treatment at the University of Massachusetts for their musculoskeletal care.
排除标准
- •Patients with a history of associated conditions such as cancer, inflammatory arthritis, or chronic alcohol or tobacco dependence will be excluded.
- •The following special populations will be excluded:
- •Adults unable to consent and/or unable to follow two-step commands
- •Individuals who are not yet adults (infants, children, teenagers)
- •Pregnant women
- •Prisoners
- •Non-English-speaking patients
结局指标
主要结局
Correlation between subchondral insufficiency fractures (SIFKs) and coexisting conditions
时间窗: 12 months
The proportion of patients with subchondral insufficiency fractures and coexisting conditions (overall and per condition) as compared to those without coexisting conditions. Coexisting conditions are identified and defined through metabolic and musculoskeletal-related findings from available lab and radiological results in the patient medical record, such as those related to diabetes, obesity, osteoarthritis and other orthopedic related conditions and metabolic issues.
次要结局
- Correlation between type of treatment for subchondral insufficiency fractures (SIFKs) and treatment outcome (pain level)(12 months)
- Correlation between activity level and treatment outcome (pain level)(12 months)
- Correlation between coexisting conditions and treatment outcome (pain level)(12 months)
研究者
Tomer Korabelnikov
Principal Investigator
University of Massachusetts, Worcester