Development of mouthwash by Thai herbs extract
Phase 3
Completed
- Conditions
- Healthy volunteers with mild-to-moderate gingivitis.Gingivitis
- Registration Number
- TCTR20210421001
- Lead Sponsor
- Research and Researchers for Industries (RRI)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 47
Inclusion Criteria
1. 18-60 years old, 2. diagnosed with mild-to-moderate gingivitis with gingival index (GI) and plaque index (PI) scores less than or equal to 2, 3. good general health, and 4. able to communicate in Thai fluently.
Exclusion Criteria
1. wear orthodontic appliances or implants, 2. presence of periodontitis, 3. use of drugs including antibiotics, anti-inflammatory, anticoagulants, anticonvulsants, im-munosuppressants and chemotherapy drugs within the past six months, 4. patholo-gies of diabetes, xerostomia, oral cancer or receiving radiation therapy, 5. smoker, 6. pregnant or breastfeeding, 7. allergic to herbs or chemical constituents in mouthwash, 8. severe alcoholism, and 9. presence of mucous membrane pemphigoid.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Gingival inflammation, Dental plaque At day 0 and day 15 of the intervention Gingival index score, Plaque index score
- Secondary Outcome Measures
Name Time Method umber of oral microorganisms At day 0 and day 15 of the intervention Spread plate method