Comparison of infection risk in trauma patients transfused with leukoreduced vs non-leukoreduced blood
Not Applicable
- Conditions
- Health Condition 1: S00-T88- Injury, poisoning and certain other consequences of external causes
- Registration Number
- CTRI/2019/08/020831
- Lead Sponsor
- AIIMS
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
all patients above 18 years of age receiving RBC transfusion within 24 hours of admission.
Exclusion Criteria
1)Patients with an anticipated survival of less than 48 hours
2)Isolated head injury patients
3)Received blood transfusion elsewhere
4)Presence of active infection
5)Pregnant females and jail inmates will be not eligible for randomization.
6)Patient with Rh(D) negative groups
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Primary outcome will include development of all hospital acquired infections [urinary tract infections (UTI), bloodstream infections (BSI), pneumonia (PNEU), ventilator-associated infections (VAE), and surgical site infections (SSI)] as defined by CDC/NHSN surveillance definitionTimepoint: Till the time of discharge or hospital death whichever is earlier
- Secondary Outcome Measures
Name Time Method Monitoring of the quantitative levels of sTREM and procalcitonin measured in all patients. <br/ ><br>Proportion of patient showing values above cut-off limit shall be considered as having infectionTimepoint: Till the time of discharge or death whichever is earlier