Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis

Not Applicable

Completed

• Conditions: Observation of Neuromuscular Block; Flexor Hallucis; Adductor Pollicis
• Interventions: Device: Monitoring Neuromuscular Blockade the Flexor Hallucis; Device: Monitoring Neuromuscular Blockade adductor of the thumb.

• Registration Number: NCT02825121
• Lead Sponsor: Poitiers University Hospital

Brief Summary

Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.

However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.

To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.

The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.

The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.

The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.

This is a prospective, exploratory, uncontrolled, single-center for routine care.

Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

Detailed Description

Not available

Study Timeline

• Study Start: 2016-02
• Study First Submitted: 2016-07-04
• Study First Submitted QC: 2016-07-04
• Study First Posted: 2016-07-07
• Status Verified: 2016-10
• Primary Completion: 2017-09
• Study Completion: 2017-09
• Last Update Submitted: 2017-10-03
• Last Update Posted: 2017-10-05

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• over 18 years
• Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time.
• ASA I or II patients
• free subject, without guardianship or subordination
• No opposition given by the patient after information

Exclusion Criteria

• under 18 years
• known neuromyopathy
• Diabetics
• Emergency surgery and a full stomach
• predictable difficult intubation
• Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Monitoring Neuromuscular Blockade	Monitoring Neuromuscular Blockade adductor of the thumb.	Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.
Monitoring Neuromuscular Blockade	Monitoring Neuromuscular Blockade the Flexor Hallucis	Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.

Primary Outcome Measures

Name	Time	Method
Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis	1 day

Trial Locations

Locations (1)

Poitiers Universitary Hospital; 🇫🇷 Poitiers, France