跳至主要内容
临床试验/NCT02825121
NCT02825121已完成不适用

Evaluation of Monitoring Neuromuscular Blockade the Flexor Hallucis Compared to the Adductor Pollicis

Poitiers University Hospital2 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2016年2月最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
60
试验地点
2
主要终点
Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis

研究概览

简要总结

Current guidelines recommend monitoring of neuromuscular blockade at the adductor pollicis by stimulation of the ulnar nerve at the wrist.

However, in certain situations (laparoscopic surgery, cranial surgery or surgical comfort, arterial catheterization), it is impossible to access the patient's wrists, delaying monitoring, antagonizing the neuromuscular block, the emergence from anesthesia and patient extubation , leading in some cases to single injections lack of control of the reversal of the patient.

To overcome these technical difficulties, a group nerve / muscle looks interesting and often easily accessible to the anesthesiologist.

The stimulation of the posterior tibial nerve can observe a response to the flexor hallucis brevis muscle and allows quick access to monitoring the reversal before the end of the intervention.

The primary outcome was to compare the speed of recovery from neuromuscular block flexor hallux versus that of the adductor pollicis.

The secondary objective was to compare the speed of installation of deep neuromuscular block flexor hallucis versus that of the adductor pollicis.

This is a prospective, exploratory, uncontrolled, single-center for routine care.

Are included all aged patients over 18 years, ASA I or II, without guardianship, having no known allergy to Atracurium, without neuromyopathy known, emergency surgery or full stomach, predictable difficult intubation .

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Single Group
主要目的
Diagnostic
盲法
None

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • over 18 years
  • Any elective surgery with single or multiple injection Atracurium for which hand and foot are accessible at the same time.
  • ASA I or II patients
  • free subject, without guardianship or subordination
  • No opposition given by the patient after information

排除标准

  • under 18 years
  • known neuromyopathy
  • Diabetics
  • Emergency surgery and a full stomach
  • predictable difficult intubation
  • Pregnant or breastfeeding women, women of childbearing age who do not have effective contraception

研究组 & 干预措施

Monitoring Neuromuscular Blockade

Experimental

Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.

干预措施: Monitoring Neuromuscular Blockade the Flexor Hallucis (Device)

Monitoring Neuromuscular Blockade

Experimental

Monitoring Neuromuscular Blockade the Flexor Hallucis and adductor of the thumb.

干预措施: Monitoring Neuromuscular Blockade adductor of the thumb. (Device)

结局指标

主要结局

Time of occurrence of a T4 / T1 ratio> 0.90 in the train of four flexor hallucis

时间窗: 1 day

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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