Dose nose rinsing with saline improve asthma in children?
Not Applicable
Recruiting
- Conditions
- Diseases of th respiratory system
- Registration Number
- KCT0001860
- Lead Sponsor
- Samsung Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
1) Written informed consent be obtained from caregivers
2) Assent from children who are 6 to 15 years of age
3) Asthma patients who are confirmed by methacholine challenge test: PC20(provocativecon centration causing 20% fall in FEV1) < 8 mg/ml or increase FEV1(Forced expiratory volume in 1 second) over 12% after using bronchodilator
Exclusion Criteria
1) Present sinusitis
2) Present nasal polyp
3) Present otitis media
4) Immotile cilia syndrome
5) Immune compromised patients
6) Severe asthma (FEV1(Forced expiratory volume in 1 second) < 60%)
7) Unable to irrigate nose due to mental retardation or cognition impairment
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of bronchial hypersensitivity by PO 20(provocativecon centration causing 20% fall in FEV1) of methacholine challenge test
- Secondary Outcome Measures
Name Time Method FeNO (fractional exhaled nitric oxide);Daily symptom diary;asthma control test;Sefum chitinase;Acoustic rhinometry;Questionnaire for Quality-of-Life Specific to the Allergic Rhinitis in Korean Children, QQOL-ARK;Rhinitis Control Assessment Test (RCAT);nasal eosinophil count