NL-OMON50402已完成不适用
Xylitol/saline nasal irrigations in patients with CRS without polyps, a multicenter double-blind, randomized study in 66 subjects with CRS without polyps - Xylitol irrigations in CRS
Isala Klinieken0 个研究点目标入组 66 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 66
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •1. Subjects must have a diagnosis of CRSsNP
- •2. Age * 18 and * 70 years.
- •3. Subjects must be willing to give Informed Consent and adhere to visit
- •schedules and medication restrictions.
排除标准
- •1. Previous surgical procedures to the paranasal sinuses
- •2. A clear dental origin of the sinus disease
- •3. Systemic or local antibiotic treatment less than 1 month before, or during
- •4. Systemic steroid treatment less than 1 month before, or during the study.
- •5. Subjects administering homeopathica to nose or paranasal sinuses.
- •6. Nasal polyps.
- •7. Subjects in whom the infection can be explained by the following reasons:
- •a. Cystic fibrosis
- •b. Congenital mucociliary problems eg. Primary Ciliary Dyskinesia
- •8. Known systemic vasculitic and granulomatous disease.
- •9. AIDS or known to be HIV positive.
- •10. Smoking (in the past 6 months).
- •11. History of radiotherapy in head and neck region.
- •12. Severe anatomic abnormalities leading to an inability to administer the
- •irrigation solution to one side of the nose (for example a severe septal
- •deviation or a large bullous middle turbinate).
- •13. Craniofacial malformations.
- •14. Abnormalities requiring other modality of therapy (obstructive polyps,
- •tumors, infection of dental origin).
- •15. Subject has a psychiatric, addictive, or any disorder that compromises
- •ability to give truly Informed Consent for participation in this study.
- •16. Patient is currently enrolled in other investigational drug trial(s) or is
- •receiving other investigational agent(s).
研究者
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