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Efficacy and Safety of Ivabradine on Top of Atenolol in Stable Angina Pectoris

Phase 3
Completed
Conditions
Angina Pectoris
Registration Number
NCT00202566
Lead Sponsor
Institut de Recherches Internationales Servier
Brief Summary

To test whether ivabradine when given in combination with atenolol is able to improve the exercise tolerance of patients with stable angina pectoris

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
750
Inclusion Criteria
  • Chronic stable angina pectoris
  • Documented coronary artery disease
  • Previous treatment with atenolol or other beta-blocker agent
  • Exercise tolerance test positivity and stability
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Exclusion Criteria
  • Heart rate < 60 bpm
  • Congestive heart failure
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Improvement between baseline and end of treatment of the treadmill exercise tolerance test
Secondary Outcome Measures
NameTimeMethod
Rate pressure product
Clinical evaluation

Trial Locations

Locations (1)

Montreal Heart Institute

🇨🇦

Montreal, Quebec, Canada

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