Does desflurane anesthesia associated or not with nitrous oxide induce genotoxicity and oxidative stress in patients?
Not Applicable
- Conditions
- Genotoxicity, oxidative stress, gene expression, polymorphism, evaluation of lipophilic antioxidants and vitaminsSP4.011.087.693.339G03.495.710E04.249G05.355.310D27.505.696.377.605.600G05.365.795.598D27.505.519.217
- Registration Number
- RBR-6jg23g
- Lead Sponsor
- Departamento de Anestesiologia
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruitment completed
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Healthy individuals who do not present other disease unless the operative condition, undergoing elective ENT and ophthalmic surgery, lasting at least 90 minutes
Exclusion Criteria
Smoking, using illicit drugs and alcohol, users of daily vitamin supplements and / or antipyretics, analgesics, antibiotics, anti-inflammatory, among others, the occupationally exposed to paints, fuel, pesticides and hospital environments, those who received radiation ionizing or MRI done in less than 30 days, those who have already undergone chemotherapy or radiotherapy, patients with diseases such as asthma, hypertension, diabetes, cancer, infectious or inflammatory processes, and those who are not referred for surgery of ENT and ophthalmology clinic.
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method