NB-UVB and PUVA Vitiligo Study

Phase 4

Completed

• Conditions: Vitiligo
• Interventions: Other: Phototherapy; Other: Phototherapy and Photochemotherapy

• Registration Number: NCT01732965
• Lead Sponsor: Henry Ford Health System

Brief Summary

To evaluate if the combination of psoralen plus ultraviolet A and narrowband ultraviolet B is more effective than narrowband ultraviolet B alone in the treatment of vitiligo.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2012-11-13
• Study First Submitted QC: 2012-11-19
• Study First Posted: 2012-11-26
• Study Start: 2013-03
• Primary Completion: 2014-01
• Study Completion: 2014-05
• Status Verified: 2017-02
• Last Update Submitted: 2017-02-22
• Last Update Posted: 2017-02-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Vitiligo affecting more than 15% body surface area.

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
NB-UVB phototherapy	Phototherapy	NB-UVB alone
phototherapy and photochemotherapy	Phototherapy and Photochemotherapy	NB-UVB and PUVA

Primary Outcome Measures

Name	Time	Method
Determine the quantity of repigmentation	6 months	Determination the degree of repigmentation measured by the VASI score (Vitiligo area Scoring Index) after treating with the combination treatments (narrowband ultraviolet B and topical psoralen plus ultraviolet A) and compare it with narrowband ultraviolet B alone.

Secondary Outcome Measures

Name	Time	Method
Determine the quality of repigmentation.	Study initiation, 3 months and 6 months.	Determination of the color of repigmentation, pattern of repigmentation, and the cessation of spread of vitiligo after treating with the combination treatments (narrowband ultraviolet B and topical psoralen plus ultraviolet A) and compare it with narrowband ultraviolet B alone.

Trial Locations

Locations (1)

Henry Ford Dermatology; 🇺🇸 Detroit, Michigan, United States