NCT01732965CompletedPhase 4
Prospective Open Parallel Right to Left Bilateral Study Comparing Narrowband Ultraviolet B Alone Versus Narrowband Ultraviolet B and Psoralen Plus Ultraviolet A for the Treatment of Vitiligo
Conditions
Trial Snapshot
- Phase
- Phase 4
- Status
- Completed
- Sponsor
- Henry Ford Health System
- Enrollment
- 10
- Locations
- 2
- Primary Endpoint
- Determine the quantity of repigmentation
Study Overview
Brief Summary
To evaluate if the combination of psoralen plus ultraviolet A and narrowband ultraviolet B is more effective than narrowband ultraviolet B alone in the treatment of vitiligo.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Vitiligo affecting more than 15% body surface area.
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Determine the quantity of repigmentation
Time Frame: 6 months
Determination the degree of repigmentation measured by the VASI score (Vitiligo area Scoring Index) after treating with the combination treatments (narrowband ultraviolet B and topical psoralen plus ultraviolet A) and compare it with narrowband ultraviolet B alone.
Secondary Outcomes
- Determine the quality of repigmentation.(Study initiation, 3 months and 6 months.)
Investigators
Iltefat Hamzavi
Senior Staff Physician
Henry Ford Health System
Study Sites (2)
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