Gedragsactivatie door de POH-GGZ versus gebruikelijke behandeling voor depressie bij oudere volwassenen in de eerste lijn.

Conditions: ate-life depression, depressive symptoms, depressie, depressieve symptomen, depressieve klachten, elderly.

Registration Number: NL-OMON20783

Lead Sponsor: Pro Persona; RadboudUMC; Radboud Universiteit

Brief Summary: Hendriks, G. J., Oude Voshaar, R. C., Keijsers, G. P., Hoogduin, C. A. and van Balkom, A. J. (2008). Cognitive-behavioural therapy for late-life anxiety disorders: a systematic review and meta-analysis. Acta Psychiatr Scand, 117, 403-411. Huibers, M. J., et al. (2014). Predicting response to cognitive therapy and interpersonal therapy, with or without antidepressant medication, for major depression: a pragmatic trial in routine practice. J Affect Disord, 152-154, 146-154. Lemmens, L. H., Arntz, A., Peeters, F., Hollon, S. D., Roefs, A. and Huibers, M. J. (2015). Clinical effectiveness of cognitive therapy v. interpersonal psychotherapy for depression: results of a randomized controlled trial. Psychol Med, 1-16. Licht-Strunk, E., Van Marwijk, H. W., Hoekstra, T., Twisk, J. W., De Haan, M. and Beekman, A. T. (2009). Outcome of depression in later life in primary care: longitudinal cohort study with three years' follow-up. BMJ, 338, a3079.

Detailed Description: Not available

Recruitment & Eligibility

Status: Other

Sex: Not specified

Target Recruitment: 200

Inclusion Criteria

The main inclusion criterion is a PHQ-9 score >9.

Exclusion Criteria

Patients will be excluded from the trial in the case of I) severe mental illness in need of specialized treatment, including severe major depression, bipolar disorder, obsessive-compulsive disorder, (history of) psychosis; II) high risk of suicide, III) drug and/or alcohol abuse or dependence, IV) prior psychotherapy received in the previous 12 weeks V) current treatment by a mental health specialist. VI) moderate to severe cognitive impairment (MoCA <18).

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Depression severity as assessed with the Quick Inventory of Depressive Symptomatology (Q-IDS) during the 8-week treatment period and follow-up.

Secondary Outcome Measures

Name	Time	Method
When proven effective, our next interest is the cost-effectiveness of BA. The EuroQol (EQ-5D-5L) and TiC-P are used.<br>Furthermore, several moderators and process variables will be investigated.