Gene involvement and correlation in head & neck cancers
Not Applicable
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2023/08/056688
- Lead Sponsor
- Sir Sunder Lal Hospital BH
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
•Histologically proven squamous cell carcinoma of head and neck excluding nasopharynx, tumors of skin, sino-nasal tract, unknown primary
Exclusion Criteria
1.Patients who has received any form of chemotherapy and radiotherapy in past
2.Pregnant or lactating women
3.Patients having previous history of cancer to any site
4.Controls having history of malignancy in the family
5.Patients having distant metastases
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Polymorphism of ERCC4 & ERCC5 genes in histologically proven newly diagnosed untreated squamous cell carcinoma of Head & Neck cancer casesTimepoint: baseline(at presentation)
- Secondary Outcome Measures
Name Time Method •Clinical correlation of polymorphism with the disease presentation, treatment outcome & treatment related toxicitiesTimepoint: 2 months