Influence of genetic variants on the outcome of critically ill patients

• Conditions: A41.9; J80.0; Sepsis, unspecified

• Registration Number: DRKS00011661
• Lead Sponsor: Klinik für Anästhesiologie und Intensivmedizin, Universitätsklinikum Essen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2014-12-31
• Study Start: 2017-03-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 272

Inclusion Criteria

ICU therapy, mechanical ventilation

Exclusion Criteria

mental disorder, immunosuppression

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Aim of this study is to analyze the 30 day mortality depending on genetic variants in ICU patients. Patients are enrolled in this study when first diagnosing Sepsis /ARDS or when they are admitted to ICU. Patients who are alive on day 30 are considered survivors. In patients who die, the day after study enclosure is documented.

Secondary Outcome Measures

Name	Time	Method
Disease severity as defined by ICU scores, like the simplified acute physiology score II (SAPS II).