Edema and Fibrosis CMR Imaging in Cardiomyopathy
- Conditions
- Cardiomyopathies
- Interventions
- Device: 7 T CMR
- Registration Number
- NCT03534726
- Lead Sponsor
- University of Pennsylvania
- Brief Summary
7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio, higher spatial resolution, and response to magnetic properties of tissue at high field. The purpose of this study is to assess the feasibility of 7 T CMR. Secondly, we wish to investigate its use, to improve clinical and research MRI. Altogether, 7 T may permit better clinical diagnosis of cardiomyopathy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ACTIVE_NOT_RECRUITING
- Sex
- All
- Target Recruitment
- 13
- Subjects between the ages of 20-70 years old
- Advanced renal disease (estimated GFR rate < 30 mL/min) or hypersensitivity to gadolinium contrast agent.
- Presence of cardiac pacemaker or implanted cardioverter defibrillator
- Pregnancy
- Inability to provide informed consent
- Other contraindications to MRI (such as claustrophobia)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Patients 7 T CMR Patients with cardiomyopathy Normal subjects 7 T CMR No prior history of heart disease.
- Primary Outcome Measures
Name Time Method ejection fraction 5 years
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
University of Pennsylvania
🇺🇸Philadelphia, Pennsylvania, United States