MedPath

Edema and Fibrosis CMR Imaging in Cardiomyopathy

Active, not recruiting
Conditions
Cardiomyopathies
Interventions
Device: 7 T CMR
Registration Number
NCT03534726
Lead Sponsor
University of Pennsylvania
Brief Summary

7 Tesla MRI is a new magnetic field strength that has become available at Penn for cardiovascular MRI. This new scanner has potential to improve assessment of cardiovascular disease due to its increased signal-to-noise ratio, higher spatial resolution, and response to magnetic properties of tissue at high field. The purpose of this study is to assess the feasibility of 7 T CMR. Secondly, we wish to investigate its use, to improve clinical and research MRI. Altogether, 7 T may permit better clinical diagnosis of cardiomyopathy.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
13
Inclusion Criteria
  • Subjects between the ages of 20-70 years old
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Exclusion Criteria
  • Advanced renal disease (estimated GFR rate < 30 mL/min) or hypersensitivity to gadolinium contrast agent.
  • Presence of cardiac pacemaker or implanted cardioverter defibrillator
  • Pregnancy
  • Inability to provide informed consent
  • Other contraindications to MRI (such as claustrophobia)
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Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Patients7 T CMRPatients with cardiomyopathy
Normal subjects7 T CMRNo prior history of heart disease.
Primary Outcome Measures
NameTimeMethod
ejection fraction5 years
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

University of Pennsylvania

🇺🇸

Philadelphia, Pennsylvania, United States

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