Safety and efficacy of mycophenolate mofetil in pediatric renal transplantatio

Completed

• Conditions: Renal transplant; Urological and Genital Diseases

• Registration Number: ISRCTN89278733
• Lead Sponsor: Erasmus Medical Center (The Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2006-12-01
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 44

Inclusion Criteria

1. All Dutch children, receiving a first kidney transplant after 01/01/2000
2. Treated with initial immunosuppression corticosteroids, MMF and CsA, during the latter part of the study with addition of basiliximab

Exclusion Criteria

1. Not on triple therapy (prednisolone/CsA/MMF) at the end of the first year
2. More than one acute rejection episode
3. Rejection episode being not steroid sensitive
4. No written informed consent

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Glomerular filtration rate<br>2. Incidence of acute rejections<br>3. Serum lipids<br>4. Blood pressure and number of antihypertensive drugs

Secondary Outcome Measures

Name	Time	Method
1. Graft survival<br>2. Incidence of malignancies<br>3. Incidence of viral infections<br>4. Incidence of anemia