Evaluation of mycophenolate mofetil and prednisolone effect as initial treatment on idiopathic membranous nephropathy
Phase 3
- Conditions
- Chronic nephritic syndrome.Chronic nephritic syndrome
- Registration Number
- IRCT20180128038539N1
- Lead Sponsor
- Ahvaz University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
Patients with nephrotic syndrome with more than 4 gr / d of proteins in 24-hour urine
changes in GFR by increase more than 30% without a known cause in serum creatinine level
patients with severe and disabling symptoms associated with nephrotic syndrome
Exclusion Criteria
systemic disease
malignancy
active infection
pregnancy
unstable angina pectoris
type I and type II diabetes
clinical evidence of renal vein thrombosis
acute gastric ulcer or gastrointestinal disease that disturbs the absorption of oral medications
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method rine protein. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Urine biochemistry test.;Albumin. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Urine biochemistry test.;Blood cholesterol. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Blood biochemistry test.;Blood creatinin. Timepoint: Before intervention and after 2, 4 and 6 month of intervention. Method of measurement: Blood biochemistry test.
- Secondary Outcome Measures
Name Time Method