Clinical Trials/NCT00746889

NCT00746889

Completed

Not Applicable

Using Ultrasound to Predict Response to Intraarticular Corticosteroids in Knee Osteoarthritis: A Randomized Placebo-Controlled Clinical Trial

University of California, San Diego2 sites in 1 country79 target enrollmentMarch 2004

ConditionsOsteoarthritis

Interventionstriamcinolone acetonide saline

Drugstriamcinolone acetonide saline

Overview

Phase: Not Applicable
Intervention: triamcinolone acetonide
Conditions: Osteoarthritis
Sponsor: University of California, San Diego
Enrollment: 79
Locations: 2
Primary Endpoint: Change in Western Ontario and McMasters Universities Arthritis Index (WOMAC) Pain Subscale
Status: Completed
Last Updated: 15 years ago

Overview Investigators Eligibility Criteria Arms & Interventions Outcomes Sites Similar Trials

Overview

Brief Summary

A study using characteristics on ultrasound to predict response to intraarticular steroid injections in patients with knee osteoarthritis. The hypothesis is that patients with inflammation on ultrasound will have a better response to corticosteroid injections compared to patients without inflammation.

Registry

clinicaltrials.gov

Start Date

March 2004

End Date

September 2008

Last Updated

15 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

University of California, San Diego

Eligibility Criteria

Inclusion Criteria

•knee pain
•diagnosis of osteoarthritis in affected knee

Exclusion Criteria

•intraarticular corticosteroids in affected knee within past three months
•primary inflammatory connective tissue disease (ie rheumatoid arthritis)
•currently taking oral corticosteroids

Arms & Interventions

Corticosteroid Injection

40 mg of intraarticular triamcinolone acetonide

Intervention: triamcinolone acetonide

Placebo Injection

Intraarticular injection of 0.9% saline

Intervention: saline

Outcomes

Primary Outcomes

Change in Western Ontario and McMasters Universities Arthritis Index (WOMAC) Pain Subscale

Time Frame: baseline to 4 weeks

WOMAC pain subscale range 0-20 (0=best, 20=worst)

Study Sites (2)

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