Comparison of Ultrasound-guided Corticosteroid Injection Versus Corticosteroid Injection and Hydrodissection for Carpal Tunnel Syndrome
Overview
- Phase
- Not Applicable
- Intervention
- Triamcinolone Acetonide
- Conditions
- Carpal Tunnel Syndrome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
- Enrollment
- 60
- Locations
- 1
- Primary Endpoint
- change from baseline in the scores on Boston Carpal tunnel Questionnaire (BQ)
- Last Updated
- 6 years ago
Overview
Brief Summary
The objective of this study is to investigate the effect of ultrasound guided steroid injection versus ultrasound guided steroid hydrodissection to treat patients with CTS.
Detailed Description
This study was a prospective, randomized clinical trial. Patients with CTS were randomly treated with sonographically guided corticosteroid injection (group A); sonographically guided hydrodissection and corticosteroid injection (group B). Boston Carpal tunnel questionnaire, nerve conduction studies and VAS pain score were performed on initial visit and after 6 weeks and 12 weeks .
Investigators
Eligibility Criteria
Inclusion Criteria
- •Clinical diagnosis of CTS The diagnosis of CTS was confirmed by electrophysiological tests.
Exclusion Criteria
- •presence of thenar atrophy any accompanying orthopedic or neurologic disorders that could mimic CTS such as cervical radiculopathy, polyneuropathy, proximal median nerve entrapment, or thoracic outlet syndrome prior steroid injection into the affected carpal tunnel within 6 months or ever received carpal tunnel surgery history of distal radius fracture pregnancy or lactation regular use of systemic NSAIDs ,corticosteroids or diuretics known allergy to corticosteroids and local anesthetics. impaired cognitive function
Arms & Interventions
steroid and hydrodissection
ultrasound guided steroid injection using 1ml of 10mg triamcinolone acetonide (Shincort) mixed with 1ml of 2% lidocaine hydrochloride (Xylocaine) and 8cc NS
Intervention: Triamcinolone Acetonide
steroid and hydrodissection
ultrasound guided steroid injection using 1ml of 10mg triamcinolone acetonide (Shincort) mixed with 1ml of 2% lidocaine hydrochloride (Xylocaine) and 8cc NS
Intervention: lidocaine hydrochloride
steroid and hydrodissection
ultrasound guided steroid injection using 1ml of 10mg triamcinolone acetonide (Shincort) mixed with 1ml of 2% lidocaine hydrochloride (Xylocaine) and 8cc NS
Intervention: normal saline
steroid only
ultrasound guided steroid injection using 1ml of 10mg triamcinolone acetonide (Shincort) mixed with 1ml of 2% lidocaine hydrochloride (Xylocaine)
Intervention: Triamcinolone Acetonide
steroid only
ultrasound guided steroid injection using 1ml of 10mg triamcinolone acetonide (Shincort) mixed with 1ml of 2% lidocaine hydrochloride (Xylocaine)
Intervention: lidocaine hydrochloride
Outcomes
Primary Outcomes
change from baseline in the scores on Boston Carpal tunnel Questionnaire (BQ)
Time Frame: 0, 6, 12 weeks.
The BQ was interviewed-administered to assess the severity of symptoms and functional status
Secondary Outcomes
- change from baseline in self reported pain intensity(0, 6, 12 weeks)
- Change from Baseline in sensory nerve conduction velocity(0, 6, 12 weeks)
- change from baseline in median nerve distal motor latency(0, 6, 12 weeks)