NCT00789646终止不适用
Painless Subconjunctival Antibiotic and Antifungal Injection in Corneal Ulcer Patients.
适应症
干预措施
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 10
- 主要终点
- Numeric rating scale
研究概览
简要总结
The propose of this study is to determine the efficacy of 2% xylocaine in reducing pain due to subconjunctival antibiotic and antifungal injection.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •The corneal ulcer patients who are diagnosed by ophthalmologist and have 2 of 3 in these following features.
- •corneal epithelial defect with stromal infiltration
- •reaction in anterior chamber
- •positive for bacteria or fungus
- •The patients have to receive subconjunctival antibiotic injection twice at least.
- •The patients must be informed consent.
排除标准
- •The patients who have history of allergy of local anesthetics, antibiotics or antifungal drugs.
- •The patients who administered NSAIDs or weak opioids within 24 hours prior to subconjunctival antibiotic/antifungal injection.
- •Unable to cooperate with the treatment.
- •Pregnant women
研究组 & 干预措施
NSS/Lidocaine
Experimental
First injection: Normal saline Second injection: 2% Lidocaine without adrenaline
干预措施: NSS/Lidocaine (Procedure)
Lidocaine/NSS
Experimental
First injection: 2% Lidocaine without adrenaline Second injection: Normal saline
干预措施: Lidocaine/NSS (Procedure)
结局指标
主要结局
Numeric rating scale
时间窗: immediately after injection
次要结局
- Side effects(24 hours after injection)
研究者
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