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Folic Acid and Omega -3 Fatty Acid Supplementation in Depressed Older Adults

Phase 2
Completed
Conditions
Depression
Registration Number
NCT00480207
Lead Sponsor
Prof. RH Belmaker
Brief Summary

Our specific aim is to determine the impact of folic acid and omega-3 supplementation on the severity of depressive symptoms among depressed adults aged 65 and above.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
15
Inclusion Criteria
  1. Age 65+ (year of birth -1942 or below)
  2. Depression (as defined by the DSM-IV diagnostic criteria for depression: major or minor depression or dysthymia)
Exclusion Criteria
  1. Co-existing psychiatric disorder (except anxiety disorders)
  2. Moderate and severe cognitive impairment
  3. Current treatment with anticoagulants, antithrombotics and fibrinolytics
  4. Current severe angina with exertion
  5. Chronic renal insufficiency
  6. Liver cirrhosis
  7. Alcohol or drug abuse

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
the severity of depressive symptomsbaseline, 4th , 8th and 12th week
Secondary Outcome Measures
NameTimeMethod
nutritional statusbaseline and end of study
possible side effectsbaseline, 4th, 8th, and 12th week
cognitive statusbaseline, 4th, 8th, and 12th week

Trial Locations

Locations (1)

Mental Health Center

🇮🇱

Beer-Sheva, Israel

Mental Health Center
🇮🇱Beer-Sheva, Israel

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