ung function and airway hyper reactivity in late preterm and term infants after severe RSV infection in comparison to healthy controls

• Conditions: J12.1; P07.2; Respiratory syncytial virus pneumonia; Extreme immaturity

• Registration Number: DRKS00004424
• Lead Sponsor: ZKJ, Universitätsklinikum Freiburg

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-12-20
• Study Completion: 2020-12-02
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting stopped after recruiting started
• Sex: All
• Target Recruitment: 5

Inclusion Criteria

for RSV group:
positive RSV-test (ELISA/ PCR in nasopharyngeal aspirate) plus any of the follwing
- wheezing
- tachypnoea > 95. percentile of age
- prolonged expiratory phase or crackles on auscultation
- cyanosis (SpO2 < 92% without oxygen)

Exclusion Criteria

-congenital heart defect
-pre-existing lung disease
-immune deficiency
-obvious skeletal thoracic malformation

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Forced expiratory flow (0.75) at one year of age<br>

Secondary Outcome Measures

Name	Time	Method
forced expiratory flow (0.75) in term an preterm infants