The Impact of Dexmedetomidine on Patients Undergoing Coronary Artery Bypass Grafting

Not Applicable

Recruiting

• Conditions: Condition 1: Coronary Artery By[pass Grafting. Condition 2: Opium Abuse.; Atherosclerosis of coronary artery bypass graft(s) and coronary artery of transplanted heart with angina pectoris; Drug abuse counseling and surveillance of drug abuser; Z71.51

• Registration Number: IRCT20150216021098N4
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 26 March 2018

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 120

Inclusion Criteria

Adult patients with oral opium abuse undergoing elective off pump coronary artery bypass grafting

Exclusion Criteria

Use of Cardiopulmonary Pump
Life threatening Arrhythmias
Massive intraoperative Bleding Requring More Than 1 Unit of Packed RBC
Use of Intraaortic Balloon Pump
Need for High Dose Vasopressors
Decline of Consent
Sensitivity to Dexmedetomidine
Ejection Fraction Less Than 30%

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Pain Severity. Timepoint: Every 1 hour. Method of measurement: NSR-CPOT.;Frequence of delireum. Timepoint: Every 8 hour. Method of measurement: ICAM.;Duration of Mechanical Ventilation. Timepoint: Every 1 hour. Method of measurement: Cornometer.;Need for Additional Opiates. Timepoint: Every 1 hour. Method of measurement: Dose Drug.

Secondary Outcome Measures

Name	Time	Method
Renal Failur. Timepoint: Daily until admitted. Method of measurement: Cratenin/ out put.