Effects of Probiotics on Constipation & Symptoms of Parkinson Disease

Phase 3

Conditions: Parkinson's Disease.
Parkinson's disease

Registration Number: IRCT20170608034390N11

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 30

Inclusion Criteria

Patients with Idiopathic Parkinson Disease
With Rome IV criteria for functional constipation
Age equal to or above 60 years
Agreed to sign the informed written consent

Exclusion Criteria

There is a contraindication to probiotics, such as previous allergies to it
Patients with active infection diagnosis
Patients being treated with antibiotics.
Patients less than 60 years
Patients receiving other probiotics
Patients who regularly use laxatives
Patients who are immunocompromised
Patients who are receiving traditional medicine products to relieve constipation.
Patients who are receiving drugs that have a high risk of constipation in the complication profile with a high risk of 10%. (Except for FDA approved drugs in the treatment of Parkinson's)

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
umber of defecation per week. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet.

Secondary Outcome Measures

Name	Time	Method
nified Parkinson's Disease Rating Scale (UPDRS). Timepoint: The beginning of the study and the end of the study. Method of measurement: Unified Parkinson's Disease Rating Scale (UPDRS) Questionnaire.;Defecation consistency. Timepoint: The beginning of the study and the end of the study. Method of measurement: Bristol stool scale.;Sensation of complete evacuation. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet.;Frequency of medication interventions to improve constipation. Timepoint: The beginning of the study and the end of the study. Method of measurement: Defecation booklet.