The effect of a mixture of probiotics on constipation symptoms in pregnant wome

• Conditions: obstruction; 10017977; constipation

• Registration Number: NL-OMON33971
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 20

Inclusion Criteria

- Pregnant women
- Constipation as defined by the Rome III criteria
- Third trimester

Exclusion Criteria

- Use of any laxatives 4 weeks before intake
- Gastro-intestinal surgery in the medical history
- Metabolic disease explaining constipation symptoms

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Primary study outcome measurement:<br /><br>- Defecation frequency<br /><br>- Episodes of difficult defecation as mentioned in the Rome III criteria</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Secondary study outcome measurements:<br /><br>- Stool consistency<br /><br>- Sensation of incomplete evacuation<br /><br>- Sensation of anorectal obstruction/ blockage<br /><br>- Manual manoeuvres to facilitate defecation<br /><br>- Abdominal pain<br /><br>- Adverse effects: bloating, flatulence, nausea, diarrhoea and bad taste<br /><br>- The presence of reflux episodes<br /><br>- The presence of uterovaginal prolapse<br /><br>- Use of Bisacodyl</p><br>