Effect of probiotics on gut microbiome and pai
Not Applicable
Recruiting
- Conditions
- The amount of pain after open heart surgery.
- Registration Number
- IRCT20110510006431N4
- Lead Sponsor
- Shahid Beheshti University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 80
Inclusion Criteria
Willingness to participate in the study and completion of informed written consent
People who, at the discretion of a cardiologist, need open heart surgery
Age over 40 years
Lack of gastrointestinal sensitivity to probiotics
Body mass index greater than 18
Do not drink alcohol or use drugs and anti-inflammatory drugs
Do not take multivitamin and mineral supplements, do not take clozapine, theophylline, caffeine, phenacetine and tacrine
Do not take interfering drugs on the surface of the intestinal microbiome
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The degree of pain. Timepoint: Immediately after regaining consciousness, 12 hours and 24 hours later regaining consciousness. Method of measurement: Visual Analog Scale.;Measurement of gut microbiome. Timepoint: Start and end of the study. Method of measurement: gut microbiome genome sequencing technique.
- Secondary Outcome Measures
Name Time Method