Blood-brain barrier leakage as a predictive factor for post-stroke epilepsy
- Conditions
- Primary acute stroke (including both cerebral infarction and hemorrhage)
- Registration Number
- NL-OMON23506
- Lead Sponsor
- Academic hospital Maastricht (azM)
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 80
In order to be eligible to participate in this study, a subject must meet all of the following criteria:
•Diagnosed with a primary acute stroke (including both cerebral infarction and hemorrhage)
•A SeLECT score = 5 or a CAVE score = 2
•Age of = 18 years
A potential subject who meets any of the following criteria will be excluded from participation in this study:
•Contradictions for a gadolinium-based contrast agent (known allergy or insufficient kidney function determined by an eGFR = 30 mL/min)
•Contradictions for MRI scanning (e.g. metal implants, cardiac pacemaker, claustrophobia, pregnancy)
•Previous history of stroke, epileptic seizures or other cerebral disorders (e.g. neurodegenerative diseases or head/brain tumors)
•Re-infarction during follow-up
•Potential epileptogenic co-morbidities (e.g. alcohol or drugs abuse, cerebral venous thrombosis, history of brain surgery)
•Absence of written informed consent (by a legal representative)
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method