Hypertensive treatment in older adults with vascular brain lesions: should we SPRINT faster?
- Conditions
- Hypertension<br />Cerebral Small Vessel Disease (CSVD)<br /><br />Hypertensie <br />Cerebrale wittestofschade
- Registration Number
- NL-OMON24551
- Lead Sponsor
- VU University Medical Centre
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
• ≥ 65 years of age
• High systolic blood pressure of 150-200mmHg based on the average of a daytime 24-hour BP (with or without taking antihypertensive medication)
Exclusion Criteria
• Medical history of diabetes mellitus
• Experienced myocardial infarction within the past 12 months
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cerebral blood flow velocity
- Secondary Outcome Measures
Name Time Method cognitive functioning, white matter lesions, orthostatic hypotension, dynamic cerebral autoregulatory capacity, CO2 responsiveness, experienced side effects, disability to reach assigned BP target