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临床试验/NCT04564170
NCT04564170已完成不适用

Characterization and Relationship Between Eating Disorders and Autism Spectrum Disorders.

Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau1 个研究点 分布在 1 个国家目标入组 135 人开始时间: 2020年4月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
135
试验地点
1
主要终点
Eating Disorders Inventory

研究概览

简要总结

This is an observational study where patients with eating disorders (ED) are compared with healthy controls without eating disorder (HC) regarding eating disorders features and autism spectrum features. Also patients will be reassessed after 5 years.

详细描述

The first author who suggested that eating disorders (EAD) and autism spectrum disorders (ASD) share common features was Christopher Gilberg in 1980. Currently it is known that patients with ED have social impairment, which is also a risk marker to develop ED, eating disturbances are overrepresented in ASD, ED and ASD have common behavioural features such as rigidity, perfectionism, and harm avoidance; and common cognitive profiles such as inflexibility, high attention to detail, high scores in systemizing profiles and poor results in advanced theory of mind tests. This relationship is also supported by similar neural phenotypes such as atypical structure and function in social brain regions found in both disorders.

The aim of the present study is to explore the relationship between ED and ASD traits in a sample of Spanish participants diagnosed with AN, bulimia nervosa (BN), binge-eating disorder (BED) and other eating disorders (OED). Specifically, the investigators aim to explore possible differences within the different ED and its particular transdiagnostic features in association with autistic traits.

The sample will consist of 90 patients with ED and 45 healthy controls (HC) without any current or lifetime history of mental disorder, both groups will be compared regarding ED and ASD features. Also patients will be reassessed in a 5 year follow up.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Being Diagnosed with ED

排除标准

  • language or intellectual impairment

结局指标

主要结局

Eating Disorders Inventory

时间窗: one year

A self report measure of Eating Disorders characteristics. Its values range from 0 to 192, higher values mean higher eating disorders symptomatology.

Autism Spectrum Quotient

时间窗: one year

A self report measure of autism traits. Its values range from 0 to 50. Higher scores mean higher autistic traits.

次要结局

  • Body Shape Questionnaire(one year)
  • Quality of Life Enjoyment and Satisfaction Questionnaire(one year)
  • State Trait Anxiety Inventory(one year)
  • Inventory of interpersonal problems personality disorder(one year)
  • Bulimic Investigatory Test Edinburgh(one year)
  • Rosenberg Self -Esteem Scale(one year)
  • Beck Depression Inventory(one year)
  • Scale Unawareness of Mental Disorders.(one year)

研究者

发起方
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
申办方类型
Other
责任方
Sponsor

研究点 (1)

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